அண்ணாத்த

Rajinikanth

'Annaatthe' Kaalaiyaan

Meena

Mangayarkarasi

Nayanthara

Pattamal

கீர்த்தி சுரேஷ்

Thanga Meenakshi

குஷ்பு சுந்தர்

Angayarkanni

Jagapati Babu

Udhav Palekar

Soori

Pachakili

Abhimanyu Singh

Manoj Palekar

ప్రకాష్ రాజ్

Nattadurai

Bala

Arjun

Livingston

Mangayarkarasi’s husband

Pandiarajan

Angayarkanni’s husband

Sathish

Angayarkanni’s brother

Sathyan Sivakumar

Mangayarkarasi’s brother

Vela Ramamoorthy

Kaalaiyan’s uncle

Billy Murali

Manoj Palekar's Henchman

Rohiet Nair

Banerjee

Mukhtar Khan

Ayyappa P. Sharma

Kulappulli Leela

Kaalaiyaan’s grandmother